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Anti-CNGA1 and CNGA3 Antibody FL594 Conjugate

Our Anti-CNGA1 and CNGA3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L36/12. It detects mouse and rat CNGA1 and CNGA3, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

This antibody recognizes both Cyclic Nucleotide Gated Channel Subunit Alpha 1 and Cyclic Nucleotide Gated Channel Subunit Alpha 3, which are both members of the cyclic nucleotide-gated cation channel family. These ion channels function in response to the binding of cyclic nucleotides. CNG channels are nonselective cation channels that are found in the membranes of various tissue and cell types, and are significant in sensory transduction as well as cellular development.

Short Description

Our Anti-CNGA1 and CNGA3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L36/12. It detects mouse and rat CNGA1 and CNGA3, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3)

Gene Name

Cnga3 Cng3

UniProt

AAO16601

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 535-637 (cytoplasmic C-terminus) of goldfish CNG (accession number AAO16601) produced recombinantly in E. Coli

Target

CNGA1 and CNGA3

Clonality

Monoclonal

Isotype

IgG1

Clone

L36/12

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/Other Ion Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

80 kDa (size will vary depending on species and isoform)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Goldfish

ICC Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939402

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