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Anti-TrpC5 Antibody FL650 Conjugate

Our Anti-TrpC5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N67/15. It is KO validated, detects guinea pig, human, mouse, and rat TrpC5, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Short transient receptor potential channel 5 or TrpC5 is encoded by the gene TRPC5. TrpC5 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. Apparent roles for Trpc5 include the regulation of neurite outgrowth. TrpC5 is found in the brain, developing fetal brain, CNS, and kidney. To date, TrpC5 functions in partnership with up to 60 proteins, including other TrpC members, IP3 receptors, NCS-1 and caveolin. Diseases associated with TrpC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis

Short Description

Our Anti-TrpC5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N67/15. It is KO validated, detects guinea pig, human, mouse, and rat TrpC5, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)

Gene Name

TRPC5 TRP5

UniProt

Q9UL62

Host

Mouse

Reactivity

Guinea Pig, Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 827-845 (SKAESSSKRSFMGPSLKKL) of human TrpC5 (accession number Q9UL62)

Target

TrpC5

Clonality

Monoclonal

Isotype

IgG2b

Clone

N67/15

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/Trp Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939391

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