What is the catalog number for Anti-GluN2B/NR2B Glutamate Receptor Antibody?

The catalog number for Anti-GluN2B/NR2B Glutamate Receptor Antibody is 75-101.

What sizes are available for Anti-GluN2B/NR2B Glutamate Receptor Antibody?

Anti-GluN2B/NR2B Glutamate Receptor Antibody is available in the following size(s): 100 µL.

Is Anti-GluN2B/NR2B Glutamate Receptor Antibody in stock?

Anti-GluN2B/NR2B Glutamate Receptor Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-GluN2B/NR2B Glutamate Receptor Antibody

Our Anti-GluN2B/NR2B glutamate receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N59/36. It is KO validated, detects human, mouse, and rat GluN2B/NR2B glutamate receptor, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

GluN2B/NR2b glutamate receptor, also known as Glutamate/N-methyl D-aspartate/NMDA receptor subtype 2B, is a member of the NMDA receptor family. NMDA receptors are expressed throughout the CNS in postsynaptic cell membranes. GluN2B is a major NMDAR subtype found in cortical and hippocampal regions of the adult brain. NMDA receptors are involved with memory and learning. Mutations in the gene encoding GluN2B are associated with autism, LennoxGastaut and West Syndromes.

Short Description

Our Anti-GluN2B/NR2B glutamate receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N59/36. It is KO validated, detects human, mouse, and rat GluN2B/NR2B glutamate receptor, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)

Gene Name

Grin2b

UniProt

Q00960

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B (accession number Q00960) produced recombinantly in E. Coli

Target

GluN2B/NR2B glutamate receptor

Clonality

Monoclonal

Isotype

IgG2b

Clone

N59/36

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.28

Molecular Weight

166 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:1000

WB Dilution

1:1000

Specificity

Does not cross-react with GluN2A/NR2A

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.