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Anti-BKbeta2 K+ Channel Antibody FL650 Conjugate

Our Anti-BKbeta2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N53/32. It detects human, mouse, and rat BKbeta2 K+ channel, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Calcium-activated potassium channel subunit beta-2, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2 or BKbeta2 is encoded by the gene KCNMB2. BKbeta2 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta2 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. BKbeta2 is expressed in the membrane in many tissues including kidney, heart, ovary and brain.

Short Description

Our Anti-BKbeta2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N53/32. It detects human, mouse, and rat BKbeta2 K+ channel, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (K (VCA) beta-2) (Maxi K channel subunit beta-2) (Slo-beta-2)

Gene Name

Kcnmb2

UniProt

Q9CZM9

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 (accession number Q9CZM9) produced recombinantly in E. Coli

Target

BKbeta2 K+ channel

Clonality

Monoclonal

Isotype

IgG2a

Clone

N53/32

Type

Primary Antibody

Applications

ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

27 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939335

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