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Anti-BKbeta4 K+ Channel Antibody

Our Anti-BKbeta4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L18A/3. It detects human, mouse, and rat BKbeta4 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Calcium-activated potassium channel subunit beta-4, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4 or BKBeta4 is encoded by the gene KCNMB4. BKbeta4 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta4 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is expressed in brain and CNS.

Short Description

Our Anti-BKbeta4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L18A/3. It detects human, mouse, and rat BKbeta4 K+ channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K (VCA) beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4)

Gene Name

Kcnmb4

UniProt

Q9JIN6

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4 (accession number Q9JIN6) produced recombinantly in E. Coli

Target

BKbeta4 K+ channel

Clonality

Monoclonal

Isotype

IgG2a

Clone

L18A/3

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.16

Molecular Weight

24 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Dilution

1:500

Specificity

No cross-reactivity against BKBeta1, BKBeta2 or BKBeta3

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2131507

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