CD44 Polyclonal Antibody
Product Specifications
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.
Abbreviation
CD44
UniProt
P26051
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Rat CD44 protein expressed by E.coli
Target
LHR; BA-1; CD44 antigen; CD44 molecule; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor ; HCELL; HAS; HUTCH1; PGP-1; Phagocytic glycoprotein 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Immunology; Stem Cells
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51kDa
Observed Molecular Weight
70-85kDa
Isotype
IgG
Available Sizes
Documents
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