(R) -10,11-Dehydrocurvularin

(R) -10,11-Dehydrocurvularin is a secondary metabolite isolated from Curvularia sp.. (R) -10,11-Dehydrocurvularin displays concentration-dependent cytotoxicity towards human tumor cell lines with a mean IC50 value of 1.25 µM[1].

Product Specifications

CAS Number

[1095588-70-7]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Antibiotic

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/10-11-dehydrocurvularin.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@H](C)CCC/C=C/1)CC2=CC(O)=CC(O)=C2C1=O

Molecular Formula

C16H18O5

Molecular Weight

290.31

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Greve H, et al. Apralactone A and a New Stereochemical Class of Curvularins from the Marine-Derived Fungus Curvularia sp. European J Org Chem. 2008;2008 (30) :10.1002/ejoc.200800522.