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Anti-Kv7.1/KCNQ1 K+ Channel Antibody (BSA and Azide free)

Selected Variant

75-081-CF

Size: 100 µL

Our carrier-free Anti-Kv7.1/KCNQ1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N37A/10. It detects hamster, human, mouse, rabbit, rat, and Xenopus Kv7.1/KCNQ1 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Potassium voltage-gated channel subfamily Q member 1 is encoded by the gene KCNQ1. KCNQ1 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.1/KCNQ1 sub-subfamily. KCNQ1 is a voltage-gated potassium channel that is required for the repolarization phase of the cardiac action potential. KCNQ1 can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. KCNQ1 is expressed in the heart, pancreas, kidney, prostate, small intestine, and peripheral blood leukocytes. Diseases associated with KCNQ1 include Long QT Syndrome1, Jervell and Lange-Nielsen Syndrome, atrial fibrillation familial 3, short QT syndrome 2, and atrial fibrillation.

Short Description

Our Anti-Kv7.1/KCNQ1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N37A/10. It detects hamster, human, mouse, rabbit, rat, and xenopus Kv7.1/KCNQ1 K+ channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1)

Gene Name

KCNQ1 KCNA8 KCNA9 KVLQT1

UniProt

P51787

Host

Mouse

Reactivity

Hamster, Human, Mouse, Rabbit, Rat, and Xenopus

Immunogen

Fusion protein amino acids 2-101 of human KCNQ1 (accession number P51787) produced recombinantly in E. Coli

Target

Kv7.1/KCNQ1 K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

N37A/10

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS

Molecular Weight

75 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

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