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Anti-Kv7.2/KCNQ2 K+ channel Antibody

Our Anti-Kv7.2/KCNQ2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N26A/23. It detects human, mouse, and rat Kv7.2/KCNQ2 K+ channel, and is tc supernatant. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Potassium voltage-gated channel subfamily Q member 2 is encoded by the gene KCNQ2. KCNQ2 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.2/KCNQ2 sub-subfamily. KCNQ2 associates with KCNQ3 to form a potassium channel with nearly identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness of synaptic inputs. KCNQ2 is expressed in the brain and spinal cord. Diseases associated with KCNQ2 include Epileptic Encephalopathy, Early Infantile, 7 and Seizures, Benign Familial Neonatal 1.

Short Description

Our Anti-Kv7.2/KCNQ2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N26A/23. It detects human, mouse, and rat Kv7.2/KCNQ2 K+ channel, and is tc supernatant. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2)

Gene Name

KCNQ2

UniProt

O43526

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2 (accession number O43526) produced recombinantly in E. Coli

Target

Kv7.2/KCNQ2 K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

N26A/23

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Rod Cell Markers/Ca2+ Channels

Concentration

Lot dependent

Format

TC Supernatant

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.9

Molecular Weight

95 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Supernatant is harvested from hybridoma cells grown under standard cell culture conditions

WB Dilution

1:1000

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

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