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Anti-TrpV3 Antibody FL650 Conjugate

Our Anti-TrpV3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N15/39. It detects human, mouse, and rat TrpV3, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Transient receptor potential cation channel subfamily V member 3 or TrpV3 is encoded by the gene TprV3. TrpV3 is a member of the transient receptor potential cation channel family. TrpV3 is thought to function in a variety of processes, including temperature sensation and vasoregulation. This channel is activated at temperatures between 22 and 40 °C. TrpV3 is found at the membrane in the CNS, PNS and skin where it acts as a transducer of thermal stimuli. Diseases associated with TRPV3 include several types of Keratoderma.

Short Description

Our Anti-TrpV3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N15/39. It detects human, mouse, and rat TrpV3, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)

Gene Name

TrpV3

UniProt

E9PU00

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3 (KTTLYAFDELDEFPETSV; accession number E9PU00)

Target

TrpV3

Clonality

Monoclonal

Isotype

IgG1

Clone

N15/39

Type

Primary Antibody

Applications

ICC

Field of Research

Ion Channels and Modulators/Trp Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939291

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