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Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody

Our Anti-Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N4/49. It detects human Pink1 PTEN induced putative kinase 1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Short Description

Our Anti-Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N4/49. It detects human Pink1 PTEN induced putative kinase 1, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

Gene Name

PINK1

UniProt

Q9BXM7

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Target

Pink1 PTEN induced putative kinase 1

Clonality

Monoclonal

Isotype

IgG1

Clone

N4/49

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Mitochondrial Biology/Neurodegenerative Disease/Parkinson's Disease

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

63 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2268255

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