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Anti-KCNU1/Slo3 pH-Sensitive Maxi-K+ Channel Antibody

Our Anti-KCNU1/Slo3 pH-sensitive maxi-K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N2/16. It is KO validated, detects mouse, Xenopus KCNU1/Slo3 pH-sensitive maxi-K+ channel, and is purified by Protein A chromatography. It is great for use in EM, ICC, IP, WB.

Product Specifications

Background

Potassium calcium-activated channel subfamily U member 1 is encoded by the gene KCNU1. KCNU1 is a member of the potassium channel family, calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily. KCNU1 is a testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates transport of K+. KCNU1 is expressed in the testis. Diseases associated with KCNU1 include Leukodystrophy, Hypomyelinating, 3 and Coffin-Siris Syndrome 1.

Short Description

Our Anti-KCNU1/Slo3 pH-sensitive maxi-K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N2/16. It is KO validated, detects mouse, xenopus KCNU1/Slo3 pH-sensitive maxi-K+ channel, and is purified by protein a chromatography. It is great for use in WB, ICC, IP, ELISA, EM.

Synonyms

Potassium channel subfamily U member 1 (Calcium-activated potassium channel subunit alpha-3) (Calcium-activated potassium channel, subfamily M subunit alpha-3) (Pore-forming subunit of the sperm-specific alkalization activated K (+) current) (KSper) (Slowpoke homolog 3) (mSlo3) (pH-sensitive maxi potassium channel)

Gene Name

Kcnu1 Kcnma3 Ksper Slo3

UniProt

O54982

Host

Mouse

Reactivity

Mouse, Xenopus

Immunogen

Fusion protein amino acids 1052-1121 of mouse Slo3 (accession number O54982) produced recombinantly in E. Coli

Target

KCNU1/Slo3 pH-sensitive maxi-K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

N2/16

Type

Primary Antibody

Applications

WB, ICC, IP, ELISA, EM

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

115 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Dilution

1:500

IP Dilution

5 μg

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2131864

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