What is the catalog number for Anti-Cavbeta4 Ca2+ Channel Antibody?

The catalog number for Anti-Cavbeta4 Ca2+ Channel Antibody is 75-054.

What sizes are available for Anti-Cavbeta4 Ca2+ Channel Antibody?

Anti-Cavbeta4 Ca2+ Channel Antibody is available in the following size(s): 100 µL.

Is Anti-Cavbeta4 Ca2+ Channel Antibody in stock?

Anti-Cavbeta4 Ca2+ Channel Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Cavbeta4 Ca2+ Channel Antibody

Our Anti-Cavbeta4 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N10/7. It detects human, mouse, pig, and rat Cavbeta4 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Voltage-dependent L-type calcium channel subunit beta-4 or Cav ß4 is encoded by the gene CACNB4. Cavß4 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß4 is expressed predominantly in the brain (cerebellum) and kidney. Diseases associated with this gene include Episodic Ataxia, Type 5 and Epilepsy.

Short Description

Our Anti-Cavbeta4 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N10/7. It detects human, mouse, pig, and rat Cavbeta4 Ca2+ channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4)

Gene Name

Cacnb4 Cacnlb4

UniProt

D4A055

Host

Mouse

Reactivity

Human, Mouse, Pig, and Rat

Immunogen

Synthetic peptide amino acids 458-474 of rat Cav4 (DENYHNERARKSRNRLS; accession number D4A055)

Target

Cavbeta4 Ca2+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

N10/7

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Ion Channels and Modulators/Ca2+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:500

WB Dilution

1:500

IP Dilution

15 μg

Specificity

No cross-reactivity against rat Cavβ1b, Cavβ2a, and Cavβ3 in transfected cells

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.