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Anti-WAVE1/SCAR Antibody

Our Anti-WAVE1/SCAR mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K91/36. It is KO validated, detects human, mouse, and rat WAVE1/SCAR, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Wiskott-Aldrich syndrome protein family member 1, Verprolin Homology Domain-Containing Protein 1, Protein WAVE-1 or SCAR1 is encoded by the gene WASF1 and is a member of the Wiskott-Aldrich syndrome protein (WASP) -family. WAVE1/SCAR is an effector protein which transmits of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1/SCAR acts as part of the WAVE complex which is involved in the regulation of actin filament reorganization and membrane ruffling. WAVE1/SCAR is expressed in many tissues including brain, ovary, colon, kidney, pancreas and thymus. Diseases associated with this gene include Wiskott-Aldrich Syndrome and Alacrima, Achalasia, And Mental Retardation Syndrome.

Short Description

Our Anti-WAVE1/SCAR mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K91/36. It is KO validated, detects human, mouse, and rat WAVE1/SCAR, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1)

Gene Name

WASF1 KIAA0269 SCAR1 WAVE1

UniProt

Q92558

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 477-498 of human Wave1/Wasp family 1 (CQVIPASEPKRHPSTLPVISDAR; accession number Q92558)

Target

WAVE1/SCAR

Clonality

Monoclonal

Isotype

IgG1

Clone

K91/36

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Cell Signaling/Cytoskeletal Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

75 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Dilution

1:1000

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2216976

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