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Anti-PICK1 Antibody FL550 Conjugate

Our Anti-PICK1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L20/8. It is KO validated, detects human, mouse, and rat PICK1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

PRKCA-binding protein or PICK1 scaffold is encoded by the gene PICK1. PICK1 is a scaffold protein which acts as an adaptor protein that binds and organizes the location of membrane proteins. Functions to cluster receptors and plays a role in synaptic plasticity. PICK1 is ubiguitously expressed and found in high levels in brain and testis. Cellularly, PICK1 is found at perinuclear region, mitochondria and synapses. Diseases associated with PICK1 include Spermatogenic Failure and Depression.

Short Description

Our Anti-PICK1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L20/8. It is KO validated, detects human, mouse, and rat PICK1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)

Gene Name

PICK1 PRKCABP

UniProt

Q9NRD5

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 10-130 of rat PICK1 (accession number AAG48152) produced recombinantly in E. Coli

Target

PICK1

Clonality

Monoclonal

Isotype

IgG2a

Clone

L20/8

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Neurodegenerative Disease/Alzheimer's Disease/Parkinson's Disease/Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

45 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2939193

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