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Anti-Co-Rest/RCOR1 Antibody FL594 Conjugate

Our Anti-Co-Rest/RCOR1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K72/8. It detects human, mouse, and rat Co-Rest/RCOR1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

REST Corepressor 1, CoREST or RCOR is encoded by the gene RCOR1 and is a member of the CoREST family of proteins. CoREST is a corepressor to the RE1 silencing transcription factor/neural restrictive silencing (REST) transcription factor and is part of a multiprotein complex (BHC complex) that represses transcription of neuron-specific genes in non-neuronal cells. This complex determines neural cell differentiation. CoREST is ubiquitously expressed in the nucleus of cells. Diseases associated with this gene include Huntington Disease and Loeys-Dietz Syndrome 1.

Short Description

Our Anti-Co-Rest/RCOR1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K72/8. It detects human, mouse, and rat Co-Rest/RCOR1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

REST corepressor 1 (Protein CoREST)

Gene Name

RCOR1 KIAA0071 RCOR

UniProt

Q9UKL0

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 109-293 of human Co-Rest (accession number Q9UKL0), includes ELM2 and SANT domains, produced recombinantly in E. Coli

Target

Co-Rest/RCOR1

Clonality

Monoclonal

Isotype

IgG1

Clone

K72/8

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Neurogenesis and Development/Transcription Regulation

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

66-80 kDa (depending on gel system used)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939190

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