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Anti-SAP97 Antibody FL594 Conjugate

Our Anti-SAP97 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.

Short Description

Our Anti-SAP97 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)

Gene Name

Dlg1 Dlgh1

UniProt

Q62696

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli

Target

SAP97

Clonality

Monoclonal

Isotype

IgG1

Clone

K64/15

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

130 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939178

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