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Anti-Kv1.6 K+ Channel Antibody FL550 Conjugate

Selected Variant

75-012-FL550

Size: 200 µL

Our Anti-Kv1.6 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K19/36. It detects human, mouse, and rat Kv1.6 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium voltage-gated channel subfamily A member 6 or Kv1.6 is encoded by the gene KCNA6. Kv1.6 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.6 is expressed in brain neurons as well as other cell types in the brain, in cardiac and smooth muscle tissue, ovary and testis.

Short Description

Our Anti-Kv1.6 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K19/36. It detects human, mouse, and rat Kv1.6 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Potassium voltage-gated channel subfamily A member 6 (RCK2) (Voltage-gated potassium channel subunit Kv1.6) (Voltage-gated potassium channel subunit Kv2)

Gene Name

Kcna6

UniProt

P17659

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide 507-525 (RERRSSYLPTPHRAYAEKR; cytoplasmic C-terminus) of rat Kv1.6 (accession number P17659)

Target

Kv1.6 K+ channel

Clonality

Monoclonal

Isotype

IgG3

Clone

K19/36

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

60 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with other Kv1 channels

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2939109

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