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Anti-Kv1.5 K+ Channel Antibody FL490 Conjugate

Selected Variant

75-011-FL490

Size: 200 µL

Our Anti-Kv1.5 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K7/45. It detects human, mouse, and rat Kv1.5 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium voltage-gated channel subfamily A member 5 or Kv1.5 is encoded by the gene KCNA5. Kv1.5 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.5 is expressed in heart, including the atria nd ventricles. Kv1.5 channels are also expressed in many other organs, such as pulmonary arteries, brain, skeletal muscle. Diseases associated with KCNA5 include Familial Atrial Fibrillation and insulinoma.

Short Description

Our Anti-Kv1.5 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K7/45. It detects human, mouse, and rat Kv1.5 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Potassium voltage-gated channel subfamily A member 5 (RCK7) (RK4) (Voltage-gated potassium channel subunit Kv1.5)

Gene Name

Kcna5

UniProt

P19024

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 542-602 (cytoplasmic C-terminus) of rat Kv1.5 (accession number P19024) produced recombinantly in E. Coli

Target

Kv1.5 K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

K7/45

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2939104

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