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Anti-Kv1.4 K+ Channel Antibody FL594 Conjugate

Our Anti-Kv1.4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K13/31. It detects human, mouse, and rat Kv1.4 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.

Short Description

Our Anti-Kv1.4 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K13/31. It detects human, mouse, and rat Kv1.4 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4)

Gene Name

Kcna4

UniProt

P15385

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide 13-37 of rat Kv1.4 (NSHMPYGYAAQARARERERLAHSR; accession number P15385)

Target

Kv1.4 K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

K13/31

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

98 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against Kv1.1, Kv1.2, Kv1.3, Kv1.5 and Kv1.6 expressed in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939102

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