Anti-Kv1.2 K+ Channel Antibody FL594 Conjugate

Kv1.2 K+ channel (Potassium voltage-gated channel subfamily A member 2), which is encoded by KCNA2 gene, is part of the Potassium voltage-gated channel family. Kv1.2 K+ channel switches between its open and closed conformation in response to the voltage difference across the membrane, which selectively allows the traffic of K+. Kv1.2 K+ channel determines potassium ion permeability of excitable membranes according to their electrochemical gradient. Therefore, this protein has for function to regulate neurotransmitter release, neuronal excitability, smooth muscle contraction, heart muscle contraction or insulin secretion. Kv1.2 is recognized as a tansmembrane/ multi-pass membrane protein. Anti-Kv1.2 K+ channel K14/16 is often used in IHC on human normal cerebral cortex.

Our Anti-Kv1.2 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K14/16. It is KO validated, detects human, mouse, and rat Kv1.2 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K (+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2)

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.