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Anti-KChIP2b K+ Channel Antibody FL650 Conjugate

Our Anti-KChIP2b K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K60/73. It detects canine, human, mouse, pig, and rat KChIP2b K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Kv channel-interacting protein 2, Kchip2 potassium channel subunit, or potassium channel auxiliary subunit KCHIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip2 is a calcium binding protein and an integral subunit component of native Kv4 channel complexes. Kchip2 is primarily expressed in heart tissue but is also found in brain. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22, Brugada Syndrome, long qt syndrome 1, and dilated cardiomyopathy.

Short Description

Our Anti-KChIP2b K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K60/73. It detects canine, human, mouse, pig, and rat KChIP2b K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2)

Gene Name

Kcnip2 Kchip2

UniProt

AAF81756

Host

Mouse

Reactivity

Canine, Human, Mouse, Pig, and Rat

Immunogen

Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756) produced recombinantly in E. Coli

Target

KChIP2b K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

K60/73

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

35 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against rat KChIPs 1,3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939079

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