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Anti-KChIP1 K+ Channel Antibody

Our Anti-KChIP1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K55/7. It detects human, mouse, non-human primate, rat, and tree shrew KChIP1 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Kv channel-interacting protein 1, Potassium Voltage-Gated Channel Interacting Protein 1 or Kchip1 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip1 associates with Kv4 alpha subunits to form native Kv4 channel complexes. Kchip1 is expressed in the brain and detected in the hippocampus and the dentate gyrus. Diseases associated with KCNIP1 include diastolic hypertension, attention deficit-hyperactivity disorder.

Short Description

Our Anti-KChIP1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K55/7. It detects human, mouse, non-human primate, rat, and tree shrew KChIP1 K+ channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1)

Gene Name

Kcnip1 Kchip1

UniProt

Q8R426

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, Rat, and Tree Shrew

Immunogen

Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426) produced recombinantly in E. Coli

Target

KChIP1 K+ channel

Clonality

Monoclonal

Isotype

IgG1

Clone

K55/7

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

30 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:500

WB Dilution

1:1000

Specificity

No cross-reactivity against rat KChIPs 2,3

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Trial Size

1

Conjugate

Unconjugated

RRID

AB_10673162

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