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Anti-CASPR/Neurexin IV Antibody

Our Anti-CASPR/Neurexin IV mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K65/35. It is KO validated, detects gerbil, human, mouse, and rat CASPR/Neurexin IV, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

CASPR (Neurexin IV) is part of the neurexin family, which includes presynaptic proteins located in the presynaptic membrane of the brain.

Short Description

Our Anti-CASPR/Neurexin IV mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K65/35. It is KO validated, detects gerbil, human, mouse, and rat CASPR/Neurexin IV, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190)

Gene Name

Cntnap1 Caspr Nrxn4

UniProt

P97846

Host

Mouse

Reactivity

Gerbil, Human, Mouse, and Rat

Immunogen

Fusion protein 1308-1381 (cytoplasmic domain) of rat Caspr (accession number P97846) produced recombinantly in E. Coli

Target

CASPR/Neurexin IV

Clonality

Monoclonal

Isotype

IgG1

Clone

K65/35

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Cell Adhesion Molecules

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

220 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:250

WB Dilution

1:1000

Specificity

No cross-reactivity reported

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2083496

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