Meclofenoxate (hydrochloride)
Meclofenoxate (Centrophenoxine) hydrochloride is an ester synthesized from DMAE and pCPA, capable of crossing the blood-brain barrier, and can stimulate memory and enhance cognition[1][2][3].
Product Specifications
CAS Number
3685-84-5
Product Name Alternative
Centrophenoxine (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR; nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/meclofenoxate-hydrochloride.html
Concentration
10mM
Purity
98.33
Solubility
DMSO : ≥ 50 mg/mL|H2O : 33.33 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(OCC(OCCN(C)C)=O)C=C1.Cl
Molecular Formula
C12H17Cl2NO3
Molecular Weight
294.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Mosharrof AH, et al. Effects of meclofenoxate and citicholine on learning and memory in aged rats. Acta Physiol Pharmacol Bulg. 1987;13 (4) :17-24.|[2]Marcer D, et al. The differential effects of meclofenoxate on memory loss in the elderly. Age Ageing. 1977 May;6 (2) :123-31.|[3]Zhang H, et al. Repurposing the Memory-promoting Meclofenoxate Hydrochloride as a Treatment for Parkinson‘s Disease through Integrative Multi-omics analysis[J]. BioRxiv, 2023: 2023.04. 07.536024.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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