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Anti-H-Ficolin Antibody

Our mouse H-Ficolin monoclonal antibody from Antibodies Incorporated is produced in-house from clone FCN334. It detects human H-Ficolin and is Protein A or Protein G purified. Works in ELISA, IP.

Product Specifications

Background

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL) -associated serine proteases) . H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

Synonyms

FCN3, FCNH, HAKA1, ficolin-3, H-ficolin, collagen/fibrinogen domain-containing lectin 3 p35, collagen/fibrinogen domain-containing protein 3, ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

Gene Name

FCN3

NCBI Gene ID

8547

UniProt

O75636

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human H-ficolin

Target

H-Ficolin

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

FCN334

Type

Primary Antibodies

Applications

ELISA, IP

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

35 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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