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Anti-Complement C5a/C5a (desArg) Anaphylatoxin Antibody

Our mouse Complement C5a/C5a (desArg) Anaphylatoxin monoclonal antibody from Antibodies Incorporated is produced in-house from clone C17/5. It detects human and non-human primate Complement C5a/C5a (desArg) Anaphylatoxin and is Protein A or Protein G purified. Works in ELISA, WB.

Product Specifications

Background

Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a (desArg) .

Synonyms

C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, anaphylatoxin C5a analog, complement component 5, prepro-C5

Gene Name

C5

NCBI Gene ID

727

UniProt

P01031

Host

Mouse

Reactivity

Human and Non-Human Primate

Immunogen

Purified human C5a

Target

Complement C5a/C5a (desArg) Anaphylatoxin

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

C17/5

Type

Primary Antibodies

Applications

ELISA, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

188 kDA (Presursor C5), 9 kDa (C5a and C5a (desArg) )

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

GAU 025-05 binds to a neoepitope exposed on C5a/C5a (desArg) .

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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