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Anti-Complement Factor D Antibody

Our mouse Complement Factor D monoclonal antibody from Antibodies Incorporated is produced in-house from clone D10/4. It detects human Complement Factor D and is Protein A or Protein G purified. Works in ELISA, WB.

Product Specifications

Background

Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.

Synonyms

CFD, ADIPSIN, ADN, DF, PFD, complement factor D, C3 convertase activator, D component of complement (adipsin), complement factor D preproprotein, properdin factor D

Gene Name

CFD

NCBI Gene ID

1675

UniProt

P00746

Host

Mouse

Reactivity

Human

Immunogen

Human factor D

Target

Complement Factor D

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

D10/4

Type

Primary Antibodies

Applications

ELISA, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

25 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

GAU 010-04 is specific for complement factor D in human serum and plasma. Epitope specificity differs from that of GAU 008-01. (1)

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

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