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Anti-Type III Collagen Antibody

Our mouse Type III Collagen monoclonal antibody from Antibodies Incorporated is produced in-house from clone 1E7-D7/Col3. It detects canine, human, kangaroo, and rat Type III Collagen and is Protein A or Protein G purified. Works in ELISA, IHC, WB.

Product Specifications

Background

Type III collagen is present in the walls of arteries, intestines and the uterus, where it strenghtens the connective tissue. Patients with defects in the type III collagen (ex. Ehlers-Danlos syndrome) are at risk of rupture of major arteries or the intestine.

Synonyms

COL3A1, EDS4A, EDSVASC, PMGEDSV, collagen alpha-1 (III) chain, Ehlers-Danlos syndrome type IV, autosomal dominant, alpha-1 type III collagen, alpha1 (III) collagen, collagen, fetal, collagen, type III, alpha 1

Gene Name

COL3A1

NCBI Gene ID

1281

UniProt

P02461

Host

Mouse

Reactivity

Canine, Human, Kangaroo, and Rat

Immunogen

Acid-digested pepsin soluble human type III collagen

Target

Type III Collagen

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

1E7-D7/Col3

Type

Primary Antibodies

Applications

ELISA, IHC, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

139 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

CSI 007-01 is highly specific for type III collagen. It has been shown to have no cross-ractivity with type I and V collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin) . Epitope is located approximately 100nm from the N-terminal of the molecule.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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