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Anti-Perlecan Antibody

Our mouse Perlecan monoclonal antibody from Antibodies Incorporated is produced in-house from clone A74. It detects bovine and human Perlecan and is Protein A or Protein G purified. Works in AP, ELISA, IHC, IP, WB.

Product Specifications

Background

Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodelling.

Synonyms

HSPG2, HSPG, PLC, PRCAN, SJA, SJS, SJS1, basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), perlecan proteoglycan

Gene Name

HSPG2

NCBI Gene ID

3339

UniProt

P98160

Host

Mouse

Reactivity

Bovine and Human

Immunogen

Bovine corneal endothelial cells

Target

Perlecan

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

A74

Type

Primary Antibodies

Applications

AP, ELISA, IHC, IP, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

400-450 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

CSI 001-74 is highly specific for perlecan. There is no evidence for cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin) . Epitope is located in domain V

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Bovine

Frequently Asked Questions

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