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Anti-Complement C3 Antibody

Our mouse Complement C3 monoclonal antibody from Antibodies Incorporated is produced in-house from clone F1-8. It detects human Complement C3 and is Protein A or Protein G purified. Works in ELISA, IP, IAP.

Product Specifications

Background

C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway.

Synonyms

C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a anaphylatoxin, acylation-stimulating protein cleavage product, complement component 3, complement component C3a, complement component C3b, epididymis secretory sperm binding protein Li 62p, prepro-C3

Gene Name

C3

NCBI Gene ID

718

UniProt

P01024

Host

Mouse

Reactivity

Human

Immunogen

Complement component 3 (C3) purified from human plasma.

Target

Complement C3

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

F1-8

Type

Primary Antibodies

Applications

ELISA, IP, IAP

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

Beta-chain (75 kDa) and an alpha-chain (110 kDa)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

CAM 008-01 is specific for human complement component 3 (C3/C3b/C3c) . The antibody CAM 008-01 reacts with the 75 kd beta-chain of the human complement factor 3.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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