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Anti-SCNN1G/Gamma-Subunit Epithelial Sodium Channel Antibody

Our mouse SCNN1G/Gamma-Subunit Epithelial Sodium Channel monoclonal antibody from Antibodies Incorporated is produced in-house from clone 5c2. It detects human SCNN1G/Gamma-Subunit Epithelial Sodium Channel and is Protein A or Protein G purified. Works in ELISA, IF, IHC, WB.

Product Specifications

Background

The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the g-subunit and putative release of a 43-amino acid inhibitory tract from the g-subunit ectodomain.

Synonyms

SCNN1G, BESC3, ENaCg, ENaCgamma, LDLS2, PHA1, PHA1B3, SCNEG, epithelial sodium channel subunit gamma, ENaC gamma subunit, ENaC subunit gamma, amiloride-sensitive epithelial sodium channel gamma subunit, amiloride-sensitive sodium channel gamma-subunit, amiloride-sensitive sodium channel subunit gamma, epithelial Na (+) channel subunit gamma, gamma-ENaC, gamma-NaCH, nonvoltage-gated sodium channel 1 subunit gamma, sodium channe epithelial 1 gamma subunit, sodium channel epithelial 1 gamma subunit, sodium channel, non-voltage-gated 1, gamma subunit, sodium channel, nonvoltage-gated 1, gamma

Gene Name

SCNN1G

NCBI Gene ID

6340

UniProt

P51170

Host

Mouse

Reactivity

Human

Immunogen

The inhibitory peptide from the human yENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human yENaC subunit.

Target

SCNN1G/Gamma-Subunit Epithelial Sodium Channel

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

5c2

Type

Primary Antibodies

Applications

ELISA, IF, IHC, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

74 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

CAM 005-02 is specific for the inhibitory tract of human yENaC subunit. The epitope differs from that of CAM 003-07.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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