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Anti-Procollagen Type IIA N-terminal Propeptide (PIIANP) Antibody

Selected Variant

BTE 003-02-04

Size: 400 uL

Our mouse Procollagen Type IIA N-terminal Propeptide (PIIANP) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 2. It detects human Procollagen Type IIA N-terminal Propeptide (PIIANP) and is Protein A or Protein G purified. Works in ELISA, IHC.

Product Specifications

Background

Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.

Synonyms

COL2A1, ACG2, ANFH, ANFH1, AOM, COL11A3, EDMMD, LCPD, OSCDP, PLSDT, SEDC, SEDSTN, SEMDSTWK, SMDALG, STL1, VPED, collagen alpha-1 (II) chain, alpha-1 type II collagen, arthroophthalmopathy, progressive (Stickler syndrome), cartilage collagen, chondrocalcin, collagen II, alpha-1 polypeptide, collagen, type II, alpha 1

Gene Name

COL2A1

NCBI Gene ID

1280

UniProt

P02458

Host

Mouse

Reactivity

Human

Immunogen

Recombinant expressed PIIANP

Target

Procollagen Type IIA N-terminal Propeptide (PIIANP)

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

2

Type

Primary Antibodies

Applications

ELISA, IHC

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

100 kDa (native trimeric), 19 kDa (monomer)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

BTE 003-02 is specific for human PIIANP. Epitope is located at the amino-terminal part of procollagen type IIA

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

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