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Anti-Procollagen Type I C-terminal Propeptide (PICP) Antibody

Our mouse Procollagen Type I C-terminal Propeptide (PICP) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 4. It detects human Procollagen Type I C-terminal Propeptide (PICP) and is Protein A or Protein G purified. Works in ELISA.

Product Specifications

Background

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organic matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum is 100-300μg/ml.

Synonyms

COL1A1, CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4, collagen alpha-1 (I) chain, alpha-1 type I collagen, alpha1 (I) procollagen, collagen Col1-ColIII-1, collagen Col1-ColIII-2, collagen alpha 1 chain type I, collagen alpha-1 (I) chain preproprotein, collagen of skin, tendon and bone, alpha-1 chain, collagen, type I, alpha 1, pro-alpha-1 collagen type 1, type I proalpha 1, type I procollagen alpha 1 chain

Gene Name

COL1A1

NCBI Gene ID

1277

UniProt

P02452

Host

Mouse

Reactivity

Human

Immunogen

PICP purified from second trimester amniotic fluid by affinity chromatography

Target

Procollagen Type I C-terminal Propeptide (PICP)

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

4

Type

Primary Antibodies

Applications

ELISA

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

100 kDa (native trimeric), 35 kDa (monomer)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

BTE 002-04 is specific for for native PICP from amniotic fluid.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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