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Anti-Oxyntomodulin Antibody

Our mouse Oxyntomodulin monoclonal antibody from Antibodies Incorporated is produced in-house from clone 46. It detects human, mouse, and rat Oxyntomodulin and is Protein A or Protein G purified. Works in ELISA.

Product Specifications

Background

Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

Gene Name

GCG

NCBI Gene ID

2641

UniProt

P01275

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic oxyntomodulin 31-37 coupled to carrier.

Target

Oxyntomodulin

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

46

Type

Primary Antibodies

Applications

ELISA

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

20 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

ABS 064-46 is specific for C-terminus of human oxyntomodulin. Does not cross-react with glucagon. ABS 064-46 has a different epitope specificity compared to ABS 064-23 and ABS 059-20.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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