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Anti-Glucagon Antibody

Our mouse Glucagon monoclonal antibody from Antibodies Incorporated is produced in-house from clone 9. It detects human, pig, and rat Glucagon and is Protein A or Protein G purified. Works in ELISA, IF, IHC.

Product Specifications

Background

Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

Gene Name

GCG

NCBI Gene ID

2641

UniProt

P01275

Host

Mouse

Reactivity

Human, Pig, and Rat

Immunogen

Synthetic C-terminal fragment of glucagon coupled to carrier

Target

Glucagon

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

9

Type

Primary Antibodies

Applications

ELISA, IF, IHC

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

20.4 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

IHC Dilution

5.597222222222222

Specificity

ABS 061-09 binds human glucagon. Cross-reacts less than 5% with oxyntomodulin. The epitope lies within the C-terminal region of glucagon.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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