Cyclophosphamide (hydrate) (Standard)

Cyclophosphamide (hydrate) (Standard) is the analytical standard of Cyclophosphamide (hydrate) . This product is intended for research and analytical applications. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

Product Specifications

CAS Number

[6055-19-2]

Product Name Alternative

Cyclophosphamide (monohydrate) (Standard)

UNSPSC

12352005

Hazard Statement

H301-H340-H350-H360

Target

DNA Alkylator/Crosslinker; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cyclophosphamide-hydrate-standard.html

Purity

99.96

Smiles

ClCCN(CCCl)P1(OCCCN1)=O.[H]O[H]

Molecular Formula

C7H17Cl2N2O3P

Molecular Weight

279.10

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Schwartz PS, et al. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells. Mol Pharmacol. 2001 Dec;60 (6) :1268-1279.|[2]al-Jafari AA, et al. Inhibition of human acetylcholinesterase by cyclophosphamide. Toxicology. 1995 Jan 19;96 (1) :1-6.|[3]Harris RN, et al. Carbon tetrachloride-induced increase in the antitumor activity of cyclophosphamide in mice: a pharmacokineticstudy. Cancer Chemother Pharmacol. 1984;12 (3) :167-72.|[4]Liu P, et al. Administration of cyclophosphamide changes the immune profile of tumor-bearing mice. J Immunother. 2010 Jan;33 (1) :53-9.