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Anti-TWIK-2 Antibody FL650 Conjugate

Our Anti-TWIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N469/28. It detects mouse TWIK-2, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Potassium two pore domain channel subfamily K member 6 is encoded by the gene KCNK6. KCNK6 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK6 is considered an open rectifier, and is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics. KCNK6 is expressed in platelets and testis. Diseases associated with KCNK6 include Thoracic Outlet Syndrome and Gingival Recession.

Short Description

Our Anti-TWIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N469/28. It detects mouse TWIK-2, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

TWIK-2 (Potassium channel subfamily K member 6) (Inward rectifying potassium channel proteinTWIK-2) (TWIK-originated similarity sequence) (TWIK-2 two-pore-domain K+ channel)

Gene Name

Kcnk6

UniProt

Q3TBV4

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 28-92 (first extracellular loop) of mouse TWIK-2 (accession number Q3TBV4) produced recombinantly in E. Coli

Target

TWIK-2

Clonality

Monoclonal

Isotype

IgG1

Clone

N469/28

Type

Primary Antibody

Applications

ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

35 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940547

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