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Anti-MMACHC Antibody FL650 Conjugate

Our Anti-MMACHC mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N230/21. It detects human and mouse MMACHC, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Metabolism of Cobalamin Associated C is encoded by the gene MMACHC. MMACHC is a member of the MMACHC family. MMACHC may have a role in the binding and intracellular trafficking of of cobalamin. MMACHC is widely expressed with higher levels in the liver, spleen, lymph nodes, thymus, and bone marrow. Diseases associated with MMACHC include Methylmalonic Aciduria and Homocystinuria, Cblc Type and Methylmalonic Acidemia with Homocystinuria.

Short Description

Our Anti-MMACHC mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N230/21. It detects human and mouse MMACHC, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Methylmalonic aciduria and homocystinuria type C protein (EC 1.16.1.-) (CblC) (Cyanocobalamin reductase (cyanide-eliminating) )

Gene Name

MMACHC

UniProt

Q9Y4U1

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Fusion protein amino acids 1-282 (full-length) of human MMACHC (accession number Q9Y4U1) produced recombinantly in E. Coli

Target

MMACHC

Clonality

Monoclonal

Isotype

IgG1

Clone

N230/21

Type

Primary Antibody

Applications

ICC

Field of Research

Rare Diseases

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

32 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939871

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