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Anti-Neuregulin-HBD (Heparin Binding Domain, Type I/II) Antibody

Our Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N120A/9. It detects human Neuregulin-HBD (Heparin binding domain, Type I/II), and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Neuregulin 1 is encoded by the gene NRG1. NRG1 is a member of the neuregulin family. NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. NRG1 is expressed in the nervous system, intestine, muscle, and heart. Diseases associated with NRG1 include Schizphrenia 6 and Lung Cancer.

Short Description

Our Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N120A/9. It detects human Neuregulin-HBD (Heparin binding domain, Type I/II), and is purified by protein a chromatography. It is great for use in ICC, ELISA.

Synonyms

Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor) ]

Gene Name

NRG1 GGF HGL HRGA NDF SMDF

UniProt

Q02297

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 14-117 (extracellular N-terminus) of human Neuregulin-1 (accession number Q02297) produced recombinantly in E. Coli

Target

Neuregulin-HBD (Heparin binding domain, Type I/II)

Clonality

Monoclonal

Isotype

IgG2a

Clone

N120A/9

Type

Primary Antibody

Applications

ICC, ELISA

Field of Research

Cell Signaling/Growth Factor Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

None Reported

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_10672368

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