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Anti-OCRL/INPP5b Antibody FL650 Conjugate

Our Anti-OCRL/INPP5b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N166A/26. It detects human, mouse, and rat OCRL/INPP5b, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Inositol polyphosphate 5-phosphatase B is encoded by the gene INPP5B. INPP5B is a member of the inositol 1,4,5-triphosphate 5-phosphatase family. INPP5B functions in the regulation of calcium signaling by inactivating inositol phosphates. INPP5B is expressed highest in the urinary bladder. Diseases associated with INPP5B include dent disease 2, lowe oculocerebrorenal syndrome, charcot-marie-tooth disease type 4j, dent disease 1, and frontotemporal dementia and/or amyotrophic lateral sclerosis 2.

Short Description

Our Anti-OCRL/INPP5b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N166A/26. It detects human, mouse, and rat OCRL/INPP5b, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)

Gene Name

INPP5B OCRL2

UniProt

Q01968

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-901 (full-length) of human OCRL (accession number Q01968) produced recombinantly in E. Coli

Target

OCRL/INPP5b

Clonality

Monoclonal

Isotype

IgG1

Clone

N166A/26

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Signaling/Parkinson's Disease

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Cross-reacts with INPP5b

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939799

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