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Anti-MMP9 Antibody FL490 Conjugate

Our Anti-MMP9 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L51/82. It detects human, mouse, and rat MMP9, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Matrix Metallopeptidase 9 is encoded by the gene MMP9. MMP9 is a member of the peptidase M10A family. MMP9 may play a role in local proteolysis of the extracellular matrix, leukocyte migration, and bone osteoclastic resorption. MMP9 cleaves type IV and V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. MMP9 is expressed in neutrophils. Diseases associated with MMP9 include Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia.

Short Description

Our Anti-MMP9 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L51/82. It detects human, mouse, and rat MMP9, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB)

Gene Name

Mmp9

UniProt

P50282

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-708 (full-length) of rat MMP9 (accession number P50282) produced recombinantly in E. Coli

Target

MMP9

Clonality

Monoclonal

Isotype

IgG2a

Clone

L51/82

Type

Primary Antibody

Applications

IHC, ICC

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

92 and 82 kDa (Pro and Active forms)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2939372

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