What is the catalog number for Anti-Pan-Shank Antibody?

The catalog number for Anti-Pan-Shank Antibody is 75-089-020.

What sizes are available for Anti-Pan-Shank Antibody?

Anti-Pan-Shank Antibody is available in the following size(s): 20 µL.

Is Anti-Pan-Shank Antibody in stock?

Anti-Pan-Shank Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Pan-Shank Antibody

Our Anti-Pan-Shank mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N23B/49. It detects human, mouse, and rat Pan-Shank, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

This antibody is a pan antibody that recognizes SH3 and multiple ankyrin repeat domains protein 1 (Shank 1), SH3 and multiple ankyrin repeat domains protein 2 (Shank 2) and SH3 and multiple ankyrin repeat domains protein 3 (Shank3) . Shank proteins act as a scaffold protein anchoring and connecting membrane bound receptors and other proteins to the cytoskeleton in neurons to enable cell signaling.

Short Description

Our Anti-Pan-Shank mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N23B/49. It detects human, mouse, and rat Pan-Shank, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon) SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (GKAP/SAPAP-interacting protein) (Proline-rich synapse-associated protein 1) (ProSAP1) (SPANK-3) SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)

Gene Name

Shank1 Shank2 Cortbp1 Kiaa1022 PROSAP1 Shank3 Kiaa1650 Prosap2 PSAP2

UniProt

Q9QX74

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (accession number Q9QX74) produced recombinantly in E. Coli

Target

Pan-Shank

Clonality

Monoclonal

Isotype

IgG1

Clone

N23B/49

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Scaffold Proteins

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.19

Molecular Weight

160 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Recognizes Shank1, Shank2 and Shank3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.