What is the catalog number for Anti-Cavbeta1 Ca2+ Channel Antibody?

The catalog number for Anti-Cavbeta1 Ca2+ Channel Antibody is 75-052.

What sizes are available for Anti-Cavbeta1 Ca2+ Channel Antibody?

Anti-Cavbeta1 Ca2+ Channel Antibody is available in the following size(s): 100 µL.

Is Anti-Cavbeta1 Ca2+ Channel Antibody in stock?

Anti-Cavbeta1 Ca2+ Channel Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Cavbeta1 Ca2+ Channel Antibody

Our Anti-Cavbeta1 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N7/18. It detects human, mouse, non-human primate, and rat Cavbeta1 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Voltage-dependent L-type calcium channel subunit beta-1 or Cav ß1 is encoded by the gene CACNB1. Cavß1 is a cytoplasmic subunit of L type voltage-sensitive calcium channels. These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cavß1 serves to regulate the activity of L-type calcium channels. Cavß1 expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Diseases associated with CACNB1 include Malignant Hyperthermia and epileptic encephalopathy.

Short Description

Our Anti-Cavbeta1 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N7/18. It detects human, mouse, non-human primate, and rat Cavbeta1 Ca2+ channel, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1)

Gene Name

CACNB1 CACNLB1

UniProt

Q02641

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, and Rat

Immunogen

Synthetic peptide amino acids 19-34 of rat Cav1 (PMEVFDPSPQGKYSKR; accession number NP_059042)

Target

Cavbeta1 Ca2+ channel

Clonality

Monoclonal

Isotype

IgG2a

Clone

N7/18

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Ion Channels and Modulators/Ca2+ Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Molecular Weight

80, 55 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:2000

WB Dilution

1:1000

IP Dilution

10 μg

Specificity

Does not cross-react with Cavβ2, Cavβ3, Cavβ4

ICC Dilution

1:2000

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.