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Anti-Complement C4c Antibody

Our mouse Complement C4c monoclonal antibody from Antibodies Incorporated is produced in-house from clone 99-72-18. It detects human Complement C4c and is Protein A or Protein G purified. Works in ELISA, IF, IHC, IP, WB.

Product Specifications

Background

C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble) . C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa) . C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.

Synonyms

C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement C4-A, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A anaphylatoxin, MHC class III region complement, Rodgers form of C4, acidic C4, acidic complement C4, complement C4A (Rodgers blood group), complement component 4A (Rodgers blood group)

Gene Name

C4A

NCBI Gene ID

720

UniProt

P0C0L4

Host

Mouse

Reactivity

Human

Immunogen

Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR) .`

Target

Complement C4c

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

99-72-18

Type

Primary Antibodies

Applications

ELISA, IF, IHC, IP, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

G-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

IHC Dilution

0.4583333333333333

Specificity

CAM 072-18 binds human complement factor C4c.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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