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Anti-Factor XII (heavy chain) Antibody

Our mouse Factor XII (heavy chain) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 10-11-5. It detects human Factor XII (heavy chain) and is Protein A or Protein G purified. Works in ELISA, WB.

Product Specifications

Background

Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.

Synonyms

F12, HAE3, HAEX, HAF, coagulation factor XII, Hageman factor, Plasma coagulation Factor XIIa, beta-factor XIIa part 1, beta-factor XIIa part 2, coagulation factor XIIa heavy chain, coagulation factor XIIa light chain

Gene Name

F12

NCBI Gene ID

2161

UniProt

P00748

Host

Mouse

Reactivity

Human

Immunogen

Affinity purified human factor XII.

Target

Factor XII (heavy chain)

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

38636

Type

Primary Antibodies

Applications

ELISA, WB

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

CAM 011-05 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. Differs from CAM 011-37.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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