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Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody

Selected Variant

ABS 033-10B-015

Size: 150 µL

Our mouse GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) monoclonal biotinylated antibody from Antibodies Incorporated is produced in-house from clone 10. It detects human GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) and is Protein A or Protein G purified. Works in ELISA.

Product Specifications

Background

Glucagon-like peptide 1 (7-36) amide (GLP-1 (7-36) amide) is the principal active form of GLP-1, the other being GLP-1 (7-37) . GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

Gene Name

GCG

NCBI Gene ID

2641

UniProt

P01275

Host

Mouse

Reactivity

Human

Immunogen

Synthetic GLP-1 (7-17)

Target

GLP-1 (7-37) and GLP-1 (7-36) amide (N-term)

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

10

Type

Primary Antibodies

Applications

ELISA

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Molecular Weight

20 kDa (proglucagon)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

ABS 033-10 binds the free N-terminus of GLP-1 (7-37) and GLP-1 (7-36) amide and shows <0.2% cross-reactivity with GLP-1 (9-36) amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1 (1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Price

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