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Anti-Peptide YY Antibody

Our mouse Peptide YY monoclonal antibody from Antibodies Incorporated is produced in-house from clone 1. It detects human Peptide YY and is Protein A or Protein G purified. Works in ELISA, IHC.

Product Specifications

Background

Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP) . While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.

Synonyms

PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY

Gene Name

PYY

NCBI Gene ID

5697

UniProt

P10082

Host

Mouse

Reactivity

Human

Immunogen

Synthetic human PYY

Target

Peptide YY

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

1

Type

Primary Antibodies

Applications

ELISA, IHC

Concentration

1 mg/mL ±15%

Format

Protein A or Protein G purified

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Molecular Weight

10 kDa (preproprotein), 5 kDa (mature pepide)

Shipping Conditions

Shipped on ice packs

Storage Conditions

2-8°C without exposure to light

Notes

BSA free

Specificity

ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.

Brand

Antibodies Inc (via BioPorto acquisition)

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

Frequently Asked Questions

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