Anti-HSCB Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
Synonyms
JAC1; Iron-sulfur cluster co-chaperone protein HscB; mitochondrial; Iron-sulfur cluster co-chaperone protein HscB; cytoplasmic; Iron-sulfur cluster co-chaperone protein HscB; HSC20
UNSPSC
41116129
HS Code
3002.1
Gene Name
HSCB
Gene ID
150274
UniProt
Q8IWL3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human HSCB recombinant protein (Position: R52-D207) .
Clonality
Polyclonal
Applications
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Liquid
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
27 kDa
Applications Notes
Optimal dilutions should be determined by end users.
Gene Name Synonym
HscB mitochondrial iron-sulfur cluster cochaperone
Protein Name
Iron-sulfur cluster co-chaperone protein HscB
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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