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Anti-KRAS Antibody Picoband® PE Conjugated

Product Specifications

Background

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Synonyms

C K RAS; c Ki ras; GTPase KRas; K Ras 2; K RAS2A; K RAS2B; K RAS4A; K RAS4B; KI RAS; KRAS; KRAS1; KRAS2; KRAS2B speicifc; Krasa; Krasb; NS3; RASK2

UNSPSC

41116129

HS Code

3002.1

Gene Name

KRAS

Gene ID

3845

UniProt

P01116

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human KRAS recombinant protein (Position: N116-M189) .

Clonality

Polyclonal

Applications

Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Liquid

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

22 kDa

Applications Notes

Optimal dilutions should be determined by end users.

Gene Name Synonym

KRAS proto-oncogene, GTPase

Protein Name

GTPase KRas

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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